There are
2,651 mi
from Reno, NV to Middletown, DE
That's the driving distance. It would take 1 day 22 hours to go from Reno, Nevada to Middletown, Delaware.
The flight distance (direct flight from Reno, NV to Middletown, DE) is 2,327.14 mi.
2,651 mi = 3.22 kms