There are
1,665 mi
from Reno, NV to Mesquite, TX
That's the driving distance. It would take 1 day 6 hours to go from Reno, Nevada to Mesquite, Texas.
The flight distance (direct flight from Reno, NV to Mesquite, TX) is 1,372.14 mi.
1,665 mi = 1.61 kms