There are
2,258 mi
from Reno, NV to Mayfield Heights, OH
That's the driving distance. It would take 1 day 14 hours to go from Reno, Nevada to Mayfield Heights, Ohio.
The flight distance (direct flight from Reno, NV to Mayfield Heights, OH) is 2,002.59 mi.
2,258 mi = 3.22 kms