There are
2,054 mi
from Reno, NV to Madisonville, KY
That's the driving distance. It would take 1 day 11 hours to go from Reno, Nevada to Madisonville, Kentucky.
The flight distance (direct flight from Reno, NV to Madisonville, KY) is 1,746.30 mi.
2,054 mi = 3.22 kms