There are
2,553 mi
from Reno, NV to Lexington, NC
That's the driving distance. It would take 1 day 21 hours to go from Reno, Nevada to Lexington, North Carolina.
The flight distance (direct flight from Reno, NV to Lexington, NC) is 2,161.04 mi.
2,553 mi = 3.22 kms