There are
2,103 mi
from Reno, NV to Jeffersonville, IN
That's the driving distance. It would take 1 day 12 hours to go from Reno, Nevada to Jeffersonville, Indiana.
The flight distance (direct flight from Reno, NV to Jeffersonville, IN) is 1,823.35 mi.
2,103 mi = 3.22 kms