There are
726 mi
from Reno, NV to Issaquah, WA
That's the driving distance. It would take 14 hours 49 mins to go from Reno, Nevada to Issaquah, Washington.
The flight distance (direct flight from Reno, NV to Issaquah, WA) is 563.78 mi.
726 mi = 1,168.06 kms