There are
353 mi
from Rancho Cucamonga, CA to Mesa, AZ
That's the driving distance. It would take 6 hours 23 mins to go from Rancho Cucamonga, California to Mesa, Arizona.
The flight distance (direct flight from Rancho Cucamonga, CA to Mesa, AZ) is 334.36 mi.
353 mi = 567.79 kms