There are
989 mi
from Raleigh, NC to Opelousas, LA
That's the driving distance. It would take 18 hours 33 mins to go from Raleigh, North Carolina to Opelousas, Louisiana.
The flight distance (direct flight from Raleigh, NC to Opelousas, LA) is 856.68 mi.
989 mi = 1,591.36 kms