There are
1,475 mi
from Provo, UT to Sikeston, MO
That's the driving distance. It would take 1 day 1 hour to go from Provo, Utah to Sikeston, Missouri.
The flight distance (direct flight from Provo, UT to Sikeston, MO) is 1,211.56 mi.
1,475 mi = 1.61 kms