Miles between Portsmouth, VA and Greenville, SC

There are
422 mi
from Portsmouth, VA to Greenville, SC

That's the driving distance. It would take 8 hours 19 mins to go from Portsmouth, Virginia to Greenville, South Carolina.

The flight distance (direct flight from Portsmouth, VA to Greenville, SC) is 367.78 mi.

422 mi = 679.50 kms