Miles between Port St Lucie, FL and Sikeston, MO

There are
999 mi
from Port St Lucie, FL to Sikeston, MO

That's the driving distance. It would take 18 hours 22 mins to go from Port St Lucie, Florida to Sikeston, Missouri.

The flight distance (direct flight from Port St Lucie, FL to Sikeston, MO) is 854.73 mi.

999 mi = 1,607.55 kms