Miles between Port St Lucie, FL and Sanford, NC

There are
651 mi
from Port St Lucie, FL to Sanford, NC

That's the driving distance. It would take 12 hours 12 mins to go from Port St Lucie, Florida to Sanford, North Carolina.

The flight distance (direct flight from Port St Lucie, FL to Sanford, NC) is 571.05 mi.

651 mi = 1,047.02 kms