Miles between Port St Lucie, FL and San Diego, CA

There are
2,542 mi
from Port St Lucie, FL to San Diego, CA

That's the driving distance. It would take 1 day 20 hours to go from Port St Lucie, Florida to San Diego, California.

The flight distance (direct flight from Port St Lucie, FL to San Diego, CA) is 2,222.78 mi.

2,542 mi = 3.22 kms