Miles between Port St Lucie, FL and Lexington, SC

There are
528 mi
from Port St Lucie, FL to Lexington, SC

That's the driving distance. It would take 9 hours 40 mins to go from Port St Lucie, Florida to Lexington, South Carolina.

The flight distance (direct flight from Port St Lucie, FL to Lexington, SC) is 466.26 mi.

528 mi = 850.09 kms