Miles between Port St Lucie, FL and Key West, FL

There are
271 mi
from Port St Lucie, FL to Key West, FL

That's the driving distance. It would take 6 hours 2 mins to go from Port St Lucie, Florida to Key West, Florida.

The flight distance (direct flight from Port St Lucie, FL to Key West, FL) is 207.82 mi.

271 mi = 436.45 kms