Miles between Port St Lucie, FL and Hilton Head Island, SC

There are
405 mi
from Port St Lucie, FL to Hilton Head Island, SC

That's the driving distance. It would take 7 hours 27 mins to go from Port St Lucie, Florida to Hilton Head Island, South Carolina.

The flight distance (direct flight from Port St Lucie, FL to Hilton Head Island, SC) is 342.19 mi.

405 mi = 652.22 kms