Miles between Port St Lucie, FL and Gainesville, FL

There are
225 mi
from Port St Lucie, FL to Gainesville, FL

That's the driving distance. It would take 4 hours 9 mins to go from Port St Lucie, Florida to Gainesville, Florida.

The flight distance (direct flight from Port St Lucie, FL to Gainesville, FL) is 203.12 mi.

225 mi = 362.73 kms