Miles between Port St Lucie, FL and Destin, FL

There are
528 mi
from Port St Lucie, FL to Destin, FL

That's the driving distance. It would take 9 hours 45 mins to go from Port St Lucie, Florida to Destin, Florida.

The flight distance (direct flight from Port St Lucie, FL to Destin, FL) is 429.48 mi.

528 mi = 849.60 kms