Miles between Port St Lucie, FL and Columbia, SC

There are
525 mi
from Port St Lucie, FL to Columbia, SC

That's the driving distance. It would take 9 hours 34 mins to go from Port St Lucie, Florida to Columbia, South Carolina.

The flight distance (direct flight from Port St Lucie, FL to Columbia, SC) is 466.40 mi.

525 mi = 844.66 kms