Miles between Port St Lucie, FL and Charleston, SC

There are
473 mi
from Port St Lucie, FL to Charleston, SC

That's the driving distance. It would take 8 hours 57 mins to go from Port St Lucie, Florida to Charleston, South Carolina.

The flight distance (direct flight from Port St Lucie, FL to Charleston, SC) is 380.91 mi.

473 mi = 760.64 kms