Miles between Port St Lucie, FL and Cayce, SC

There are
519 mi
from Port St Lucie, FL to Cayce, SC

That's the driving distance. It would take 9 hours 27 mins to go from Port St Lucie, Florida to Cayce, South Carolina.

The flight distance (direct flight from Port St Lucie, FL to Cayce, SC) is 464.20 mi.

519 mi = 835.25 kms