Miles between Port St Lucie, FL and Beaufort, SC

There are
412 mi
from Port St Lucie, FL to Beaufort, SC

That's the driving distance. It would take 7 hours 36 mins to go from Port St Lucie, Florida to Beaufort, South Carolina.

The flight distance (direct flight from Port St Lucie, FL to Beaufort, SC) is 356.73 mi.

412 mi = 663.19 kms