Miles between Port St Lucie, FL and Anniston, AL

There are
641 mi
from Port St Lucie, FL to Anniston, AL

That's the driving distance. It would take 11 hours 39 mins to go from Port St Lucie, Florida to Anniston, Alabama.

The flight distance (direct flight from Port St Lucie, FL to Anniston, AL) is 548.35 mi.

641 mi = 1,030.88 kms