There are
1,307 mi
from Port St Lucie, FL to Agawam, MA
That's the driving distance. It would take 1 day to go from Port St Lucie, Florida to Agawam, Massachusetts.
The flight distance (direct flight from Port St Lucie, FL to Agawam, MA) is 1,111.53 mi.
1,307 mi = 1.61 kms