There are
520 mi
from Poplar Bluff, MO to Seagoville, TX
That's the driving distance. It would take 9 hours 10 mins to go from Poplar Bluff, Missouri to Seagoville, Texas.
The flight distance (direct flight from Poplar Bluff, MO to Seagoville, TX) is 450.15 mi.
520 mi = 837.37 kms