There are
2,090 mi
from Poplar Bluff, MO to San Mateo, CA
That's the driving distance. It would take 1 day 13 hours to go from Poplar Bluff, Missouri to San Mateo, California.
The flight distance (direct flight from Poplar Bluff, MO to San Mateo, CA) is 1,750.75 mi.
2,090 mi = 3.22 kms