There are
417 mi
from Poplar Bluff, MO to New Lenox, IL
That's the driving distance. It would take 7 hours 43 mins to go from Poplar Bluff, Missouri to New Lenox, Illinois.
The flight distance (direct flight from Poplar Bluff, MO to New Lenox, IL) is 353.31 mi.
417 mi = 670.39 kms