There are
539 mi
from Poplar Bluff, MO to Midlothian, TX
That's the driving distance. It would take 9 hours 31 mins to go from Poplar Bluff, Missouri to Midlothian, Texas.
The flight distance (direct flight from Poplar Bluff, MO to Midlothian, TX) is 477.40 mi.
539 mi = 866.79 kms