Miles between Poplar Bluff, MO and Kirksville, MO

There are
346 mi
from Poplar Bluff, MO to Kirksville, MO

That's the driving distance. It would take 6 hours 51 mins to go from Poplar Bluff, Missouri to Kirksville, Missouri.

The flight distance (direct flight from Poplar Bluff, MO to Kirksville, MO) is 265.41 mi.

346 mi = 557.39 kms