Miles between Pittsburgh, PA and Cape Girardeau, MO

There are
645 mi
from Pittsburgh, PA to Cape Girardeau, MO

That's the driving distance. It would take 12 hours 28 mins to go from Pittsburgh, Pennsylvania to Cape Girardeau, Missouri.

The flight distance (direct flight from Pittsburgh, PA to Cape Girardeau, MO) is 555.74 mi.

645 mi = 1,038.10 kms