There are
1,221 mi
from Pearland, TX to La Crosse, WI
That's the driving distance. It would take 22 hours 25 mins to go from Pearland, Texas to La Crosse, Wisconsin.
The flight distance (direct flight from Pearland, TX to La Crosse, WI) is 1,008.62 mi.
1,221 mi = 1.61 kms