There are
1,976 mi
from Palo Alto, CA to Hannibal, MO
That's the driving distance. It would take 1 day 10 hours to go from Palo Alto, California to Hannibal, Missouri.
The flight distance (direct flight from Palo Alto, CA to Hannibal, MO) is 1,662.04 mi.
1,976 mi = 3,180.41 kms