There are
1,637 mi
from Palmdale, CA to Sioux Falls, SD
That's the driving distance. It would take 1 day 4 hours to go from Palmdale, California to Sioux Falls, South Dakota.
The flight distance (direct flight from Palmdale, CA to Sioux Falls, SD) is 1,299.96 mi.
1,637 mi = 1.61 kms