There are
2,410 mi
from Palmdale, CA to Roanoke, VA
That's the driving distance. It would take 1 day 18 hours to go from Palmdale, California to Roanoke, Virginia.
The flight distance (direct flight from Palmdale, CA to Roanoke, VA) is 2,129.54 mi.
2,410 mi = 3,878.14 kms