There are
1,418 mi
from Palmdale, CA to Mesquite, TX
That's the driving distance. It would take 1 day 1 hour to go from Palmdale, California to Mesquite, Texas.
The flight distance (direct flight from Palmdale, CA to Mesquite, TX) is 1,241.18 mi.
1,418 mi = 1.61 kms