There are
1,590 mi
from Palmdale, CA to Maryville, MO
That's the driving distance. It would take 1 day 3 hours to go from Palmdale, California to Maryville, Missouri.
The flight distance (direct flight from Palmdale, CA to Maryville, MO) is 1,331.02 mi.
1,590 mi = 1.61 kms