There are
2,060 mi
from Palmdale, CA to Jeffersonville, IN
That's the driving distance. It would take 1 day 12 hours to go from Palmdale, California to Jeffersonville, Indiana.
The flight distance (direct flight from Palmdale, CA to Jeffersonville, IN) is 1,808.71 mi.
2,060 mi = 3.22 kms