There are
2,298 mi
from Palmdale, CA to Greenwood, SC
That's the driving distance. It would take 1 day 16 hours to go from Palmdale, California to Greenwood, South Carolina.
The flight distance (direct flight from Palmdale, CA to Greenwood, SC) is 2,039.21 mi.
2,298 mi = 3.22 kms