There are
2,356 mi
from Palmdale, CA to Cayce, SC
That's the driving distance. It would take 1 day 17 hours to go from Palmdale, California to Cayce, South Carolina.
The flight distance (direct flight from Palmdale, CA to Cayce, SC) is 2,103.37 mi.
2,356 mi = 3.22 kms