There are
2,588 mi
from Palmdale, CA to Canandaigua, NY
That's the driving distance. It would take 1 day 22 hours to go from Palmdale, California to Canandaigua, New York.
The flight distance (direct flight from Palmdale, CA to Canandaigua, NY) is 2,250.80 mi.
2,588 mi = 3.22 kms