There are
2,496 mi
from Palm Desert, CA to Niagara Falls, NY
That's the driving distance. It would take 1 day 20 hours to go from Palm Desert, California to Niagara Falls, New York.
The flight distance (direct flight from Palm Desert, CA to Niagara Falls, NY) is 2,102.93 mi.
2,496 mi = 4,016.72 kms