There are
1,756 mi
from Palm Desert, CA to Edwardsville, IL
That's the driving distance. It would take 1 day 6 hours to go from Palm Desert, California to Edwardsville, Illinois.
The flight distance (direct flight from Palm Desert, CA to Edwardsville, IL) is 1,507.54 mi.
1,756 mi = 2,826.55 kms