There are
647 mi
from Palatine, IL to Canandaigua, NY
That's the driving distance. It would take 12 hours 29 mins to go from Palatine, Illinois to Canandaigua, New York.
The flight distance (direct flight from Palatine, IL to Canandaigua, NY) is 550 mi.
647 mi = 1,041.79 kms