There are
814 mi
from Owensboro, KY to Lexington, NE
That's the driving distance. It would take 15 hours 9 mins to go from Owensboro, Kentucky to Lexington, Nebraska.
The flight distance (direct flight from Owensboro, KY to Lexington, NE) is 705.92 mi.
814 mi = 1,309.23 kms