There are
372 mi
from Overland Park, KS to Sioux Falls, SD
That's the driving distance. It would take 6 hours 41 mins to go from Overland Park, Kansas to Sioux Falls, South Dakota.
The flight distance (direct flight from Overland Park, KS to Sioux Falls, SD) is 332.71 mi.
372 mi = 598.93 kms