There are
726 mi
from Ottumwa, IA to Mesquite, TX
That's the driving distance. It would take 13 hours 57 mins to go from Ottumwa, Iowa to Mesquite, Texas.
The flight distance (direct flight from Ottumwa, IA to Mesquite, TX) is 615.01 mi.
726 mi = 1,169.15 kms