There are
452 mi
from Oshkosh, WI to St Charles, MO
That's the driving distance. It would take 8 hours 28 mins to go from Oshkosh, Wisconsin to St Charles, Missouri.
The flight distance (direct flight from Oshkosh, WI to St Charles, MO) is 375.86 mi.
452 mi = 727.04 kms