There are
361 mi
from Orland Park, IL to Paducah, KY
That's the driving distance. It would take 6 hours 38 mins to go from Orland Park, Illinois to Paducah, Kentucky.
The flight distance (direct flight from Orland Park, IL to Paducah, KY) is 316.67 mi.
361 mi = 580.94 kms