There are
640 mi
from Omaha, NE to Owensboro, KY
That's the driving distance. It would take 12 hours 5 mins to go from Omaha, Nebraska to Owensboro, Kentucky.
The flight distance (direct flight from Omaha, NE to Owensboro, KY) is 530.88 mi.
640 mi = 1,030.77 kms